AFSSA

Agence Française de Sécurité Sanitaire des Aliments
AFSSA-site de Ploufragan 

 
The “Agence Française de Sécurité Sanitaire des Aliments” (French Food Safety Agency – AFSSA) is a governmental organisation reporting to three Ministries, Health, Agriculture and Consumer affairs. The Agency’s objective is to ensure food safety, from the production of safe animal and safe products through distribution to the consumer. Thus the Agency has also specific responsibilities in animal health and welfare, and veterinary medicines. The Ploufragan laboratory (LERAP) conducts research, gives scientific and technical support, and delivers expert reports in respect of poultry, rabbit and pig productions and the products thereof. The general goal of LERAP is to identify new pathogens involved either in animal health or in veterinary public health including food safety. It is also to improve prevention regarding those diseases and to contribute to a better knowledge of their pathogenesis
 
Five recent relevant publications:

1. N. Naffakh, P. Massin, N. Escriou, B. Crescenzo-Chaigne, and S. van der Werf (2000) "Genetic analysis of the compatibility between polymerase proteins from human and avian strains of influenza A viruses" J. Gen. Virol., 81, 1283-91.
2. P. Massin, S. van der Werf, and N. Naffakh (2001) "Residue 627 of PB2 is determinant for cold-sensitivity of RNA replication of avian influenza viruses" J. Virol., 75, 5398-404.
3. N. Naffakh, P. Massin, and S. van der Werf (2001) "The transcription/replication activity of the polymerase of influenza A viruses is not correlated with the level of proteolysis induced by the PA subunit" Virology, 285, 244-52.
4. P. Massin, P. Rodrigues, M. Marasescu, S. van der Werf, and N. Naffakh (2005) "Cloning of the chicken RNA polymerase I promoter and use for reverse genetics of influenza A viruses in avian cells" J. Virol., 79, 13811-6.
5. Y. Blanchard, N. Le Meur, M. Le Cunff, P. Blanchard, J. Léger, A. Jestin. Cellular Gene Expression Survey of PseudoRabies Virus (PRV) Infection of Human Embryonic Kidney Cells (HEK-293). Under press Vet. Research

Website:

• afssa

---

Print this page